Calcium-binding properties of human fibrin(ogen) and degradation products
نویسندگان
چکیده
منابع مشابه
Fibrinogen-fibrin degradation products.
The identification of the molecular structure of fibrinogen has given a better understanding of many clinical conditions associated with abnormalities of fibrinogen. Proteolysis of fibrinogen or fibrin by its natural lytic enzyme, plasmin, leads to the formation of degradation products which are of great importance in the laboratory diagnosis of many pathological conditions. The biochemical and...
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An increase in low molecular weight fibrin-fibrinogen degradation products (FDP) was demonstrated in cerebrospinal fluid (CSF) from 17 of 18 patients with bacterial or viral meningitis compared with 29 patients without meningitis. The CSF also showed an increase in coagulation proteins of molecular weight less than 90000 (factors VII, IX, and plasminogen) but did not contain fibrinogen (MW 3400...
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The isolation and characterization of carp (Cyprinus carpio) plasma fibrinogen and its plasmin degradation products are described. Alike other vertebrate species, carp fibrinogen is a dimeric protein and consists of three different pairs of disulfide-bonded polypeptide chains. Aa, B/f, and y. In contrast to mammalian fibrinogen, the B0 chain of carp fibrinogen has apparently a higher molecular ...
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The serum and urine concentrations of fibrin/fibrinogen degradation products (F.D.P.) were estimated in 172 patients with glomerulonephritis. In each case the diagnosis was established on the basis of clinical, renal histological, and ultrastructural findings. Serum F.D.P. concentrations were often raised in all types of glomerulonephritis, though more consistently in active proliferative forms...
متن کاملStructure of plasmic degradation products of human fibrinogen. Fibrinopeptide and polypeptide chain analysis.
Direct determination of fibrinopeptides A and B in purified plasmic degradation products of human fibrinogen shows that fibrinogen and Fragments X and Y contain 2 moles of fibrinopeptide A per mole; Fragment E has approximately 0.3 mole of fibrinopeptide A per mole. Fibrinopeptide B is present in only trace amount in some Fragment X preparations and is absent from Fragments Y and E. Fragment D ...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1979
ISSN: 0014-5793
DOI: 10.1016/0014-5793(79)80194-5